Product Name: Cytover
Active substance: Liothyronine Sodium
Thyroid hormone, levorotatory isomer triyodtirozina makes up for the deficit of thyroid hormones. Increase in oxygen demand of tissues, stimulates their growth and differentiation, and increases the basal metabolic rate (proteins, fats and carbohydrates). In small doses, has an anabolic, and in large - catabolic effect. Inhibits the production of TSH. Enhances energy processes, positive effect on the nervous system, cardiovascular system, liver and kidneys. The maximum pharmacological effect develops within 2-3 days.
Hypothyroidism (primary, secondary), myxedema, cretinism, cerebral pituitary with hypothyroid disease state, hypothyroid obesity, endemic and sporadic goiter (relapse prevention), thyroid cancer, diagnosis of hypothyroidism.
Contraindications and Cautions:
Hypersensitivity, untreated hyperthyroidism, coronary heart disease (myocardial infarction, angina III-IV FC), myocarditis, untreated adrenal insufficiency. Tachycardia, tachyarrhythmia, angina I-II FC, heart failure, diabetes, advanced age. Not suitable for long-term therapy. In the appointment of indirect anticoagulants and oral hypoglycemic drugs should be monitored for the clotting time of blood and blood glucose levels.
Allergic reactions, the progression of heart failure and stenokardia. Overdose Symptoms: thyrotoxicosis (palpitations, arrhythmias (including tachycardia), increased sweating, anxiety, irritability, weight loss, increased appetite, diarrhea, tremors, fever, vomiting, headache, and dysmenorrhea). Treatment: induction vomiting activated charcoal, symptomatic treatment.
Liothyronin taken orally 30 minutes before eating. When hypothyroid states appoint 25 mg / day, if necessary, increase the dose to 25 mg / day every 1-2 weeks, the maintenance dose - 25-75 mg / day. When myxedema initial dose - 5 mg / day every 1-2 weeks raised to 5-10 mcg when the dose of 25 mg / day increased further performed on 5-25 mg / day every 1-2 weeks. The maintenance dose is 50-100 mg / day. If a nontoxic goiter primary dose (5 mg / day) increased by 5-10 mg every 1-2 weeks, the maintenance dose - 75 mg / day. Cretinism: initial dose of 5 mg / day and then to increase the dose of 5 mg / day every 3-4 days to achieve the effect. Suppressive test with T3: increased uptake of 131I in the thyroid gland is administered in a dose of 75-100 mg / day for 7 days, then repeat the test. Children and the elderly initial dose of 5 mg / day, then it was gradually increased by 5 mg / day.
Reduces the effect of hypoglycemic drugs, increases - anticoagulants, vasoconstrictor drugs. Cholestyramine reduces the absorption. Oral contraceptives reduce the effect. Phenytoin, salicylates, dicumarol, furosemide (at high doses), clofibrate, antidepressants, cardiac glycosides, ketamine increase the concentration and the risk of side effects liothyronine.
At a temperature of 15-25 ° C. Keep out of the reach of children.